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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DGKZ All Species: 11.21
Human Site: T477 Identified Species: 18.97
UniProt: Q13574 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.23
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13574 NP_001099010.1 1117 124128 T477 R P F I I R P T P S P L M K P
Chimpanzee Pan troglodytes XP_508395 1117 124129 T477 R P F I I R P T P S P L M K P
Rhesus Macaque Macaca mulatta XP_001102461 1084 120447 T444 R P F I I R P T P S P L M K P
Dog Lupus familis XP_540755 766 85714 F203 G F Q Q K F T F H S K E I V A
Cat Felis silvestris
Mouse Mus musculus Q80UP3 929 104029 D366 G W I L S T L D Q L R L K P P
Rat Rattus norvegicus O08560 929 103991 D366 G W I L S T L D Q L R L K P P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513139 955 107141 L392 P D L P P E E L D D G V H K L
Chicken Gallus gallus NP_001026363 953 106222 T390 V A I L P L G T G N D L A R T
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001922445 1086 121319 G461 L A R T L N W G G G Y T D E P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q09103 1457 160124 I805 R A F I V K P I P S P E V I P
Honey Bee Apis mellifera XP_396522 837 92900 L274 P L G T G N D L A R A L G W G
Nematode Worm Caenorhab. elegans Q10024 937 105180 P374 L K E M I V P P T W I L R L A
Sea Urchin Strong. purpuratus XP_796061 815 92455 T252 C T L G V H A T I I I P P T W
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q39017 728 79965 D165 E G A D Q T D D S S F C S Y C
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 90.3 65.1 N.A. 78.2 79.3 N.A. 54.7 67.8 N.A. 60.4 N.A. 31.9 31.2 31.6 43.1
Protein Similarity: 100 99.8 91.2 66.6 N.A. 80.5 80.5 N.A. 65.8 74.8 N.A. 70.6 N.A. 46.1 46.2 46.3 55
P-Site Identity: 100 100 100 6.6 N.A. 13.3 13.3 N.A. 6.6 13.3 N.A. 6.6 N.A. 53.3 6.6 20 6.6
P-Site Similarity: 100 100 100 13.3 N.A. 20 20 N.A. 13.3 33.3 N.A. 20 N.A. 73.3 6.6 26.6 13.3
Percent
Protein Identity: N.A. N.A. N.A. 20.5 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 32.9 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 22 8 0 0 0 8 0 8 0 8 0 8 0 15 % A
% Cys: 8 0 0 0 0 0 0 0 0 0 0 8 0 0 8 % C
% Asp: 0 8 0 8 0 0 15 22 8 8 8 0 8 0 0 % D
% Glu: 8 0 8 0 0 8 8 0 0 0 0 15 0 8 0 % E
% Phe: 0 8 29 0 0 8 0 8 0 0 8 0 0 0 0 % F
% Gly: 22 8 8 8 8 0 8 8 15 8 8 0 8 0 8 % G
% His: 0 0 0 0 0 8 0 0 8 0 0 0 8 0 0 % H
% Ile: 0 0 22 29 29 0 0 8 8 8 15 0 8 8 0 % I
% Lys: 0 8 0 0 8 8 0 0 0 0 8 0 15 29 0 % K
% Leu: 15 8 15 22 8 8 15 15 0 15 0 58 0 8 8 % L
% Met: 0 0 0 8 0 0 0 0 0 0 0 0 22 0 0 % M
% Asn: 0 0 0 0 0 15 0 0 0 8 0 0 0 0 0 % N
% Pro: 15 22 0 8 15 0 36 8 29 0 29 8 8 15 50 % P
% Gln: 0 0 8 8 8 0 0 0 15 0 0 0 0 0 0 % Q
% Arg: 29 0 8 0 0 22 0 0 0 8 15 0 8 8 0 % R
% Ser: 0 0 0 0 15 0 0 0 8 43 0 0 8 0 0 % S
% Thr: 0 8 0 15 0 22 8 36 8 0 0 8 0 8 8 % T
% Val: 8 0 0 0 15 8 0 0 0 0 0 8 8 8 0 % V
% Trp: 0 15 0 0 0 0 8 0 0 8 0 0 0 8 8 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 8 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _